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Events at the neuromuscular junction nmj. In order for a muscle to contract all six steps must occur in sequence as a continuous process. The neuromuscular junction nmj is a specialized synapse forming the primary connection between a lower motor neuron and a skeletal muscle fiber. Assemble the nmj you have learned about the six events at the neuromuscular junction. Muscles require innervation to function and even just to maintain muscle tone avoiding atrophy. Choose from 220 different sets of neuromuscular junction events at flashcards on quizlet. Published on jun 10 2019 this video explains the events at the neuromuscular junction nmj from the motor neuron action potential to the generation of the action potential on the muscle cell. It allows the motor neuron to transmit a signal to the muscle fiber causing muscle contraction.

Ach binding opens ion channels in the receptors that allow simultaneous passage of na into the muscle fiber and k out of the muscle fiber. Axon terminal of myelinated axon neuromuscular of motor neuron junction action potential sarcolemma ap of the muscle nucleus fiber figure 1 1. Maintaining robust function of the nmj is critical for healthy muscular contraction and movement with disruption of the nmj being recognized as an important and early pathological event in spinal muscular atrophy sma. This chapter provides an. When an ap reaches the nmj is released o causes the permeability of the sarcolemma to change which causes a change in membrane potential. More na ions enter than k ions exit which produces a local change in membrane potential called the end plate potential.

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